Lesión renal aguda y rabdomiólisis por consumo de cocaína esnifada: Caso clínico
Acute kidney injury and rhabdomyolysis due to sniffed cocaine use
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Introducción: El consumo de cocaína es un problema creciente en Colombia. Las alteraciones que se producen por su consumo son variadas, llegando a ser mortales por sobredosis. Caso clínico: Se presenta el caso de un hombre joven que posterior a consumo de grandes cantidades de cocaína esnifada presenta rabdomiólisis con lesión renal aguda, el cual a pesar del manejo médico óptimo progresó a urgencia dialítica por lo que amerita soporte renal con hemodiálisis. Días más tarde recuperó la función renal y logró ser egresado sin requerimiento de la continuidad de la diálisis. Conclusión: Los mecanismos de la lesión renal aguda producida por cocaína aún no están bien descritos. Las opciones terapéuticas utilizadas para su tratamiento siguen siendo la hidratación y, en caso de lesión renal aguda complicada, la diálisis.
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Center for Behavioral Health Statistics S. Key Substance Use and Mental Health Indicators in the United States: Results from the 2020 National Survey on Drug Use and Health. 2021.
Zimmerman JL. Cocaine Intoxication. Crit Care Clin. 2012 Oct;28(4):517–26.
Boletín Estadístico 2021 — Prevalencia del consumo de drogas | www.emcdda.europa.eu [Internet]. [cited 2023 Jan 8]. Available from: https://www.emcdda.europa.eu/data/stats2021/gps_en
Encuesta nacional de consumo de sustancias psicoactivas (ENCSPA) [Internet]. [cited 2023 Jan 8]. Available from: https://www.dane.gov.co/index.php/estadisticas-por-tema/salud/encuesta-nacional-de-consumo-de-sustancias-psicoactivas-encspa
JIMÉNEZ-OSPINA L, ZAPATA-OSPINA JP, PINEDA-ÁLVAREZ M, QUINTERO-AGUIRRE J, JIMÉNEZ-OSPINA L, ZAPATA-OSPINA JP, et al. Characteristics and complications of acute cocaine intoxication. A cross-sectional study in an emergency room in Colombia. Acta Medica Colombiana [Internet]. 2022 Oct 15 [cited 2023 Jan 8];47(1):22–30. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-24482022000100022&lng=en&nrm=iso&tlng=en
Carrasco R, Salinas M, Rossel V. Rabdomiólisis e insuficiencia renal aguda por consumo de cocaína: Caso clínico. Rev Med Chil. 2011 Apr;139(4):480–3.
Gossop M, Griffiths P, Powis B, Strang J. Cocaine: patterns of use, route of administration, and severity of dependence. Br J Psychiatry [Internet]. 1994 [cited 2023 Jan 8];164(5):660–4. Available from: https://pubmed.ncbi.nlm.nih.gov/7921717/
Nzerue CM, Hewan-Lowe K, Riley LJ. Cocaine and the kidney: a synthesis of pathophysiologic and clinical perspectives. Am J Kidney Dis [Internet]. 2000 Jan 1 [cited 2023 Jan 8];35(5):783–95. Available from: https://pubmed.ncbi.nlm.nih.gov/10793010/
Kannan L. Renal manifestations of recreational drugs: A narrative review of the literature. Medicine [Internet]. 2022 Dec 16 [cited 2023 Jan 8];101(50):e31888. Available from: https://pubmed.ncbi.nlm.nih.gov/36550840/
Gitman MD, Singhal PC. Cocaine-induced renal disease. Expert Opin Drug Saf [Internet]. 2004 Sep [cited 2023 Jan 8];3(5):441–8. Available from: https://pubmed.ncbi.nlm.nih.gov/15335299/
Pendergraft WF, Herlitz LC, Thornley-Brown D, Rosner M, Niles JL. Nephrotoxic effects of common and emerging drugs of abuse. Clin J Am Soc Nephrol [Internet]. 2014 [cited 2023 Jan 8];9(11):1996–2005. Available from: https://pubmed.ncbi.nlm.nih.gov/25035273/
Jahir T, Hossain SMS, Risal R, Schmidt M, Enriquez D, Bagum M. Cocaine Hurts Your Kidneys Too: A Rare Case of Acute Interstitial Nephritis Caused by Cocaine Abuse. Cureus. 2021 Nov 3.
Filho JCCL, Ogawa MY, de Souza Andrade TH, de Andrade Cordeiro Gadelha S, Fernandes PFCBC, Queiroz AL, et al. Spectrum of acute kidney injury associated with cocaine use: Report of three cases. BMC Nephrol. 2019 Mar 20;20(1).
Goel N, Pullman JM, Coco M. Cocaine and kidney injury: a kaleidoscope of pathology. Clin Kidney J [Internet]. 2014 Dec 1 [cited 2023 Jan 8];7(6):513–7. Available from: https://pubmed.ncbi.nlm.nih.gov/25859366/
Gupta A, Thorson P, Penmatsa KR, Gupta P. Rhabdomyolysis: Revisited. Ulster Med J [Internet]. 2021 May 1 [cited 2023 Jan 8];90(2):61. Available from: /pmc/articles/PMC8278949/
Horowitz BZ, Panacek EA, Jouriles NJ. Severe rhabdomyolysis with renal failure after intranasal cocaine use. Journal of Emergency Medicine [Internet]. 1997 Nov [cited 2023 Jan 8];15(6):833–7. Available from: https://pubmed.ncbi.nlm.nih.gov/9404801/
Mudoni A, Caccetta F, Caroppo M, Musio F, Accogli A, Zacheo MD, et al. Acute kidney injury and rhabdomyolysis after cocaine overdose: case report and literature review. G Ital Nefrol. 2018 Mar 1;35(2).
Singh S. Possible cocaine-induced acute renal failure without rhabdomyolysis Science and Human Rights View project Inhaled anticholinergics and cardiovascular risk View project [Internet]. Article in Journal of Nephrology. 2006. Available from: https://www.researchgate.net/publication/7255657
Amoedo ML, Craver L, Marco MP, Fernandez E. Cocaine-induced acute renal failure without rhabdomyolysis. Nephrology Dialysis Transplantation [Internet]. 1999 Dec 1 [cited 2023 Jan 8];14(12):2970–1. Available from: https://academic.oup.com/ndt/article/14/12/2970/1818779
