Virus chikungunya: ¿qué sabemos de esta arbovirosis?
Virus chikungunya: ¿qué sabemos de esta arbovirosis?
Barra lateral del artículo
PDF
FLIP
Contenido principal del artículo
Resumen
Introducción: para Colombia el virus Chikungunya (CHIKV) se constituye en un potencial problema de salud pública, debido a que en el país tanto en ámbitos rurales como urbanos es endémica la presencia del mosquito A. Aegypti, vector de la infección, el mismo del virus del dengue.
Objetivo: realizar revisión temática referente al CHIKV y al síndrome febril que
ocasiona.
Metodología: revisión bibliográfica descriptiva, con búsqueda en las bases de datos: PubMed, Scopus, ScienceDirect, OvidSP y Medline; incluyendo artículos de revisión, reportes de casos y estudios experimentales.
Resultados: se encontraron 107 artículos, de los cuales se utilizaron 78 documentos a conveniencia: revisiones, informes de investigación, reportes de casos, boletines e
informes epidemiológicos.
Conclusiones: el CHIKV es un Alphavirus con un solo serotipo identificado, una de las 29 especies pertenecientes al género Alphavirus de la familia Togaviridae. Posee dos ciclos de transmisión, uno selvático o enzoótico y otro urbano o epizoótico. El período de incubación varía entre uno y doce días. Fiebre alta, rash cutáneo y severo dolor osteoarticular, son las características clínicas que cursan en seis días, con baja letalidad y difícil diferenciar de otras enfermedades tropicales, incluidas malaria y dengue.
En la mayoría de los casos se adquiere inmunidad permanente. El tratamiento es sintomático y no existe vacuna disponible. Las autoridades sanitarias deben fortalecer los programas de control vectorial, para hacer frente a esta enfermedad. Rev.cienc. biomed. 2014;5(2):317-328.
Palabras clave:
Descargas
Detalles del artículo
Referencias (VER)
Lumsden WHR. An epidemic of virus disease in Southern Province, Tanganyika territory, in 1952–1953 II. General description and epidemiology. Trans R Soc Trop Med Hyg.
;49(1):33-57.
Robinson MC. An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. I. Clinical features. Trans R Soc Trop Med Hyg. 1955;49(1):28-32.
Enserink M. Massive Outbreak Draws Fresh Attention to Little-Known Virus. Science. 2006;311(5764):1085.
Hammon WM. History of mosquito-borne haemorrhagic fever. Bulletin of the World Health Organization. 1966;35(1):35-37.
Organización Panamericana de la Salud OMdlS. Número de casos reportados de chikungunya en países o territorios de las Américas 2013-2014. 2014 26/09/2014.
Sarkar JK. Virological studies of haemorrhagic fever in Calcutta. Bul World Health Organ. 1966;35(1):59.
Aikat BK, Konar NR, Banerjee G. Haemorrhagic Fever in Calcutta Area. Indian J. Med Res. 1964;52:660-675.
Sergon K, Njuguna C, Kalani R, Ofula V, Onyango C, Konongoi LS, et al. Seroprevalence of Chikungunya virus (CHIKV) infection on Lamu Island, Kenya, October 2004. Am J Trop Med Hyg. 2008;78(2):333-337.
Kariuki M, Nderitu L, Ledermann JP, Ndirangu A, Logue CH, Kelly CH, et al. Tracking epidemic Chikungunya virus into the Indian Ocean from East Africa. J Gen Virol. 2008;89(Pt 11):2754-
Beltrame A, Angheben A, Bisoffi Z, Monteiro G, Marocco S, Calleri G, et al. Imported Chikungunya Infection, Italy. Emerg Infect Dis. 2007;13(8):1264-1266.
Schwartz O, Albert ML. Biology and pathogenesis of chikungunya virus. Nature Reviews Microbiology. 2010;8(7):491-500.
Angelini R, Finarelli AC, Angelini P, Po C, Petropulacos K, Macini P, et al. An outbreak of chikungunya fever in the province of Ravenna, Italy. Eurosurveillance. 2007;12(9):E0709061.
Cordel H, Quatresous I, Paquet C, Couturier E. Imported cases of chikungunya in metropolitan France, April 2005February 2006.Eurosurveillance. 2006;11(4):E0604203.
Krastinova E, Quatresous I, Tarantola A. Imported cases of chikungunya in metropolitan France: update to June 2006. Eurosurveillance. 2006;11(8):E0608241.
Grandadam M, Caro V, Plumet S, Thiberge JM, Souares Y, Failloux AB, et al. Chikungunya virus, southeastern France. Emerg Infect Di. 2011;17(5):910-913.
SIVIGILA. Chikungunya Boletín Epidemiológico, evento prioritario. Boletín diario No.13. Boletín. Colombia: Instituto Nacional de Salud, prioritario E;2014 29/09/2014.
Powers AM, Brault AC, Tesh RB, Weaver SC. Re-emergence of Chikungunya and O’nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. Journal Gen Virol. 2000;81(Pt 2):471-479.
Solignat M, Gay B, Higgs S, Briant L, Devaux C. Replication cycle of chikungunya: a re-emerging arbovirus. Virology. 2009;393(2):183-197.
Porterfield J. Antigenic characteristics and classification of the Togaviridae. En Schlesinger, R (Ed), The Togaviruses. New York: Academic Press. 1980:13-46.
King AMQ, Adams MJ, Lefkowitz EJ, Carstens EB. Virus Taxonomy: Classification and Nomenclature of Viruses : Ninth Report of the International Committee on Taxonomy of Viruses: Elsevier; 2012.
Calisher CH, Karabatsos, N. Arbovirus serogroups: definition and geographic distribution. En: Monath TP, editor. The Arboviruses: Epidemiology and Ecology. I. Boca Raton, FL: CRC Press; 1998. p. 19-57.
Powers AM, Brault AC, Shirako Y, Strauss EG, Kang W, Strauss JH, et al. Evolutionary relationships and systematics of the alphaviruses. J Virol. 2001;75(21):10118-10131.
Weaver SC, Winegar R, Manger ID, Forrester NL. Alphaviruses: Population genetics and determinants of emergence. Antiviral research. 2012;94(3):242-257.
Strauss JH, Strauss EG. The alphaviruses: gene expression, replication, and evolution. Microbiological reviews. 1994;58(3):491-562.
Khan AH, Morita K, Parquet Md Mdel C, Hasebe F, Mathenge EG, Igarashi A. Complete nucleotide sequence of chikungunya virus and evidence for an internal polyadenylation site. J Gen Virol.
;83(Pt 12):3075-3084.
Razmy AM. Clinical features of chikungunya infection in Sri Lanka. Asian Pac J Tropl Dis. 2014;4(2):131-134.
Borgherini G, Poubeau P, Staikowsky F, Lory M, Moullec NL, Becquart JP, et al. Outbreak of Chikungunya on Reunion Island: Early Clinical and Laboratory Features in 157 Adult Patients.
Clin Infect Dis. 2007;44(11):1401-1407.
Touret Y, Randrianaivo H, Michault A, Schuffenecker I, Kauffmann E, Lenglet Y, et al. Early maternal-fetal transmission of the Chikungunya virus. La Presse Médicale. 2006;35(11, Part
:1656-1658.
Robillard P-Y, Boumahni B, Gérardin P, Michault A, Fourmaintraux A, Schuffenecker I, et al. Transmission verticale materno-foetale du virus chikungunya: Dix cas observés sur l’île de la Réunion chez 84 femmes enceintes. La Presse Médicale. 2006;35(5, Part 1):785-788.
Gerardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, et al. Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Reunion.
PLoS medicine. 2008;5(3):e60.
Couderc T, Gangneux N, Chrétien F, Caro V, Le Luong T, Ducloux B, et al. Chikungunya Virus Infection of Corneal Grafts. J Infect Dis. 2012;206(6):851-859.
Staikowsky F, Talarmin F, Grivard P, Souab A, schffenecker I. Prospective study of chikungunya virus acute infection in the Island of La Reunion during the 2005-2006 outbreak. PLoS ONE
(10): e7603 doi:101371/journalpone0007603 19893613.
Paty MC. The expansion of vector-borne diseases and the implications for blood transfusion safety: The case of West Nile Virus, dengue and chikungunya. Transfus Clin Biol. 2013;20(2):165-173.
Bernard E, Solignat M, Gay B, Chazal N, Higgs S, Devaux C, et al. Endocytosis of chikungunya virus into mammalian cells: role of clathrin and early endosomal compartments. PLoS One. 2010;5(7):e11479.
Thiberville SD, Moyen N, Dupuis-Maguiraga L, Nougairede A, Gould EA, Roques P, et al. Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy. Antiviral research.
;99(3):345-370.
Jose J, Snyder JE, Kuhn RJ. A structural and functional perspective of alphavirus replication and assembly. Future Microbiol. 2009;4(7):837-856.
Leung JY, Ng MM, Chu JJ. Replication of alphaviruses: a review on the entry process of alphaviruses into cells. Adv Virol. 2011;2011:249640.
Diallo M, Thonnon J, Traore-Lamizana M, Fontenille D. Vectors of Chikungunya virus in Senegal: current data and transmission cycles. Am J Trop Med Hyg. 1999;60(2):281-286.
Thiboutot MM, Kannan S, Kawalekar OU, Shedlock DJ, Khan AS, Sarangan G, et al. Chikungunya: a potentially emerging epidemic? PLoS neglected tropical diseases. 2010;4(4):e623.
Caglioti C, Lalle E, Castilletti C, Carletti F, Capobianchi MR, Bordi L. Chikungunya virus infection: an overview. New Microbiol. 2013;36(3):211-227.
Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S. A single mutation in Chikungunya virus affects vector specificity and epidemic potential. PLoS pathogens. 2007;3(12):e201.
Vazeille M, Moutailler S, Coudrier D, Rousseaux C, Khun H, Huerre M, et al. Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection
in the mosquito, Aedes albopictus. PLoS One. 2007;2(11):e1168.
Burt FJ, Rolph MS, Rulli NE, Mahalingam S, Heise MT. Chikungunya: a re-emerging virus. Lancet. 2012; 379(9816):662-671.
Das T, Jaffar-Bandjee MC, Hoarau JJ, Krejbich Trotot P, Denizot M, Lee-Pat-Yuen G, et al. Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus. Prog Neurobiol.
;91(2):121-129.
Sissoko D, Malvy D, Giry C, Delmas G, Paquet C, Gabrie P, et al. Outbreak of Chikungunya fever in Mayotte, Comoros archipielago, 2005–2006. Trans R Soc Trop Med Hyg. 2008;102(8):780-786.
Chang K, Hsieh H-C, Tsai J-J, Lin W-R, Lu P-L, Chen Y-H. Diagnosis and management of imported Chikungunya fever in Taiwan: a case report. The Kaohsiung J Med Sci. 2010;26(5):256-260.
Powers AM, Logue CH. Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus. J Gen Virol. 2007;88(Pt 9):2363-2377.
Larrieu S, Pouderoux N, Pistone T, Filleul L, Receveur M-C, Sissoko D, et al. Factors associated with persistence of arthralgia among chikungunya virus-infected travellers: Report of 42 French
cases. J Clin Virol. 2010;47(1):85-88.
Haas H, Robin S, Ramful D, Houdon L, Minodier P, Gérardin P. Chikungunya virus infections in children. Arch Pedatr. 2009;16, Supplement 2(0):S72-S9.
Borgherini G, Poubeau P, Jossaume A, Gouix A, Cotte L, Michault A, et al. Persistent Arthralgia Associated with Chikungunya Virus: A Study of 88 Adult Patients on Reunion Island. Clin Infect
Dis. 2008;47(4):469-475.
Mohd Zim MA, Sam IC, Omar SFS, Chan YF, AbuBakar S, Kamarulzaman A. Chikungunya infection in Malaysia: Comparison with dengue infection in adults and predictors of persistent
arthralgia. J Clin Virol. 2013;56(2):141-145.
Priya R, Khan M, Rao MK, Parida M. Cloning, expression and evaluation of diagnostic potential of recombinant capsid protein based IgM ELISA for chikungunya virus. J Virol Methods.
;203(0):15-22.
Simon F, Paule P, Oliver M. Chikungunya Virus–Induced Myopericarditis: Toward an Increase of Dilated Cardiomyopathy in Countries with Epidemics? Am J Trop Med Hyg. 2008;78(2):212-213.
Chandak NH, Kashyap RS, Kabra D, Karandikar P, Saha SS, Morey SH, et al. Neurological complications of Chikungunya virus infection. NeurolIndia. 2009;57(2):177-180.
C Wa, Monredon, Md Jd, Amrani, Md Me, Roger. Guillain-barre syndrome complicating a Chikungunya virus infection. Neurology. 2007;69(22):2105-2107.
Singh SS, Manimunda SP, Sugunan AP, Sahina N, Vijayachari P. Four cases of acute flaccid paralysis associated with chikungunya virus infection. Epidemiol Infec. 2008;136(09):1277-1280.
Manimunda SP, Mavalankar D, Bandyopadhyay T, Sugunan AP. Chikungunya epidemic-related mortality. Epidemiol Infect. 2011;139(9):1410-1412.
Instituto Nacional de Salud MdSyPS. Lineamientos de Vigilancia en Salud Pública Entomologica y de Laboratorio en Transmisión Autóctona del Virus Chikungunya en Colombia FASE II. Colombia:
Instituto Nacional de Salud; 2014.
Pfeffer M, Linssen B, Parker MD, Kinney RM. Specific Detection of Chikungunya Virus Using a RT-PCR/Nested PCR Combination. J Vet Med B Infect Dis Vet Public Health. 2002;49(1):49-52.
Hasebe F, Parquet MC, Pandey BD, Mathenge EGM, Morita K, Balasubramaniam V, et al. Combined detection and genotyping of Chikungunya virus by a specific reverse transcription-polymerase
chain reaction. J Med Virol. 2002;67(3):370-374.
Kularatne SA, Gihan MC, Weerasinghe SC, Gunasena S. Concurrent outbreaks of Chikungunya and Dengue fever in Kandy, Sri Lanka, 2006-07: a comparative analysis of clinical and laboratory features. Postgraduate medical journal. 2009;85(1005):342-346.
Ravichandran R, Manian M. Ribavirin therapy for Chikungunya arthritis. J Infect Dev Ctries. 2008;2(2):140-142.
Briolant S, Garin D, Scaramozzino N, Jouan A, Crance JM. In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral compounds: synergistic effect of interferon-alpha and ribavirin combination. Antiviral Res. 2004;61(2):111-117.
Delogu I, de Lamballerie X. Chikungunya disease and chloroquine treatment. Journal of Medical Virology. 2011;83(6):1058-1059.
Brighton SW. Chloroquine phosphate treatment of chronic Chikungunya arthritis. An open pilot study. SA Mediese Tydskrif Deel. 1984;66(6):217-218.
Edelman R, Tacket CO, Wasserman SS, Bodison SA, Perry JG, Mangiafico JA. Phase II safety and immunogenicity study of live chikungunya virus vaccine TSI-GSD-218. Am J Trop Med Hyg.
;62(6):681-685.
White A, Berman S, Lowenthal JP. Comparative immunogenicities of Chikungunya vaccines propagated in monkey kidney monolayers and chick embryo suspension cultures. Applied microbiology. 1972;23(5):951-952.
Wang E, Volkova E, Adams AP, Forrester N, Xiao SY, Frolov I, et al. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine. 2008;26(39):5030-5039.
Tiwari M, Parida M, Santhosh SR, Khan M, Dash PK, Rao PV. Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of
Chikungunya virus. Vaccine. 2009;27(18):2513-2522.
Sharma A, Raviv Y, Puri A, Viard M, Blumenthal R, Maheshwari RK. Complete inactivation of Venezuelan equine encephalitis virus by 1,5-iodonaphthylazide. Biochemical and biophysical research communications. 2007;358(2):392-398.
Wang D, Suhrbier A, Penn-Nicholson A, Woraratanadharm J, Gardner J, Luo M, et al. A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia
and arthritis. Vaccine. 2011;29(15):2803-2809.
Kumar M, Sudeep AB, Arankalle VA. Evaluation of recombinant E2 protein-based and wholevirus inactivated candidate vaccines against chikungunya virus. Vaccine. 2012;30(43):6142-
Citado por
