Hamartoma mesenquimatoso hepático gigante

Luis Alfonso Caicedo-Caicedo, Lissette Lorena Guevara-Flórez, Heidy Marsiglia-Armella, Mario Jaimes-Gutiérrez

Resumen


 Introducción: el hamartoma mesenquimatoso hepático (HMH) es un tumor poco frecuente en la infancia, cuya etiología está relacionada con alteraciones del desarrollo embrionario del hígado.

Caso clínico: se describe un caso de HMH en una lactante mayor, con imágenes diagnósticas que sugerían hepatoblastoma. Se realizó biopsia hepática demostrando HMH, se descartaron patologías malignas y se realizó resección completa del tumor. La paciente evolucionó satisfactoriamente.

Conclusión: en el diagnóstico diferencial del HMH hay que considerar el hepatoblastoma, en especial cuando se presenta con pobre componente quístico. La ecografía, la tomografía de abdomen y en especial la resonancia magnética son herramientas diagnósticas; la resección operatoria es el tratamiento adecuado. Rev.cienc.biomed. 2016;7(1):128-132.

PALABRAS CLAVE

Hamartoma; Neoplasias hepáticas; Mesenquimatoso.

SUMMARY

Introduction: hepathic mesenchymal harmatoma is an uncommon tumor during the chilhood whose etiology is related to alterations in the embryonic development of the liver.

Case report: it is described a hepathic mesenchymal hamartoma case in a female older infant with images that suggested hepatoblastoma. It was carried out a liver biopsy to show hepathic mesenchymal hamartoma to reject malign pathologies and complete resection of the tumor. The patient made a satisfactory recovery.

Conclusion: the hepatoblastoma should be considered in the differential diagnosis of hepathic mesenchymal hamartoma, specially when it comes with poor cystic component. The ultrasound, abdomen tomography and magnetic resonance spectroscopy are diagnostic tools; resection is the appropriate treatment. Rev.cienc. biomed. 2016;7(1):128-132.

KEYWORDS

Hamartoma; Liver neoplasms; Mesenchymal.


Texto completo:

Sin título

Referencias


Vargas-Vallejo MP, Álvarez-Solís RM, Cabrera-Aguirre J, Bulnes-Mendizábal DP, Ulloa-Patiño P.

Hamartoma mesenquimatoso hepático gigante en una niña de 2 años. An Pediatr.2005;63: 564-5.

Masood A. Siddiqui, MD; Barbara J. McKenna, MD. Hepatic Mesenchymal Hamartoma, A Short

Review. Arch Pathol Lab Med. 2006;130: 1567–69.

Wolfgang S, Philip G. Nonmalignant tumors of the liver. In: Arnold G. Coran. Pediatric Surgery.

Seventh Edition. 2012;32: 459-62.

Rich-Barrie S, La Q, Michael P. Hepatic tumors in childhood. In: Jarnagin, William R., MD, FACS.

Blumgart’s surgery of the liver, biliary tract and pancreas. Fifth Edition. 2012;82:132-43.

Linda F. Benign and malignant tumors of the liver. In: Odze and Goldblum Surgical Pathology

of the GI Tract, Liver, Biliary Tract and Pancreas. Third Edition. 2015;55:1539-72.

Pablo RR, Sukru ME. Benign tumors of the liver. In: Richard M. Gore MD, Marc S. Levine MD.

Textbook of Gastrointestinal Radiology. Fourth Edition. 2015; 86:1528-60.

Klein-Moreira R, Washington K. Liver neoplasms. In: Christine A. Lacobuzio-Donahue and

Elizabeth Montgomery. Gastrointestinal and liver pathology. Second edition. 2012;20:626-77.

Tomlinson GE. Hepatoblastoma and other liver tumors in children. In: Nathan and Oski’s

Hematology and Oncology of Infancy and Childhood. Eighth Edition. 2015;58:1886-1905.

Murthi GV, Paterson L, Azmy A. Chromosomal translocation in mesenchymal hamartoma of

liver: what is its significance? Journal of Pediatric Surgery. 2003; 38(10):1543-45.

Mathews J, Eric J. Duncavage JD. Pfeifer. Characterization of translocations in mesenchymal

hamartoma and undifferentiated embryonal sarcoma of the liver. Experimental and molecular

pathology. 2013; 95:319–24.

Ramanujam JC, Ramesh DW, Goh KT, Wong W.A. Ariffin, G. Kumar, and N.A. Taib. Malignant

transformation of mesenchymal hamartoma of the liver: case report and review of the

literature. Journal of Pediatric Surgery.1999;34(11):1684-86.

G Nair, M Fortier and Y Low. Cystic hepatic mesenchymal hamartoma: the role of radiology in

diagnosis and perioperative management. The British Journal of Radiology. 2011;84:91–4.

Mark D. Stringer, Naved K. Alizai. Mesenchymal hamartoma of the liver: a systematic review.

Journal of Pediatric Surgery.2005:40:1681–90.


Enlaces refback

  • No hay ningún enlace refback.


Revista Ciencias Biomedicas
ISSN 2215-7840 / ISSN-e 2389-7252

Universidad de Cartagena
Facultad de Medicina Zaragocilla cra 50C # 24-120

6698177-6698178

correo-e:revistacienciasbiomedicas@unicartagena.edu.co